INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15
Peptide Drug Conjugates : A new hope to improve Cancer Management
Authors Name:
Mr.Kamlesh S Pathak
, Dr.Santosh Jain , Ms.P.M.Raut
Unique Id:
IJSDR2312092
Published In:
Volume 8 Issue 12, December-2023
Abstract:
Cancer remains the leading cause of death worldwide despite advances in treatment options for patients. As such, safe and effective therapeutics are required. Short peptides provide advantages to be used in cancer management due to their unique properties, amazing versatility, and progress in biotechnology to overcome peptide limitations. Several appealing peptide- based therapeutic strategies have been developed. Here, we provide an overview of peptide conjugates, the better equivalents of antibody-drug conjugates, as the next generation of drugs for required precise targeting, enhanced cellular permeability, improved drug selectivity, and reduced toxicity for the efficient treatment of cancers. We discuss the basic components of drug conjugates and their release action, including the release of cytotoxins from the linker. We also present peptide-drug conjugates under different stages of clinical development as well as regulatory and other challenges.
Keywords:
short peptides; peptide-drug conjugates; drug delivery; cancer; Linkers; nanotechnology
Cite Article:
"Peptide Drug Conjugates : A new hope to improve Cancer Management", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 12, page no.710 - 715, December-2023, Available :http://www.ijsdr.org/papers/IJSDR2312092.pdf
Downloads:
000338719
Publication Details:
Published Paper ID: IJSDR2312092
Registration ID:209631
Published In: Volume 8 Issue 12, December-2023
DOI (Digital Object Identifier):
Page No: 710 - 715
Publisher: IJSDR | www.ijsdr.org
ISSN Number: 2455-2631
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