INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15
The process of a solid dissolving in a liquid phase to create a homogenous mixture is known as solubility. A crucial factor in getting the right quantity of drug into the bloodstream to show a pharmacological effect is solubility. Low water solubility of the novel therapeutic compound is the main issue with formulation. Poorly aqueous soluble medications need substantial dosages to reach their maximum therapeutic plasma concentration after oral delivery. Using the biopharmaceutical classification system (BCS), substances are categorized according to their solubility and permeability. Regulatory agencies and health organizations have adopted this categorization system to enable dissolution to be used to verify bioequivalence for highly soluble and highly permeable chemicals. Drugs with poor water solubility dissolve slowly, which reduces their bioavailability when taken orally. This review article aims to increase bioavailability and promote efficient absorption.
"Method to boost solubility", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.9, Issue 1, page no.404 - 409, January-2024, Available :http://www.ijsdr.org/papers/IJSDR2401059.pdf
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000338719
Publication Details:
Published Paper ID: IJSDR2401059
Registration ID:209869
Published In: Volume 9 Issue 1, January-2024
DOI (Digital Object Identifier):
Page No: 404 - 409
Publisher: IJSDR | www.ijsdr.org
ISSN Number: 2455-2631
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