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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | A DETAIL OVERVIEW ON PHYTOCHEMISTRY, PHARMACOGNOSY AND PHARMACOLOGY OF MAIDENHAIR TREE (Ginkgo biloba L). |
| Authors Name: | Mayur Dattatray Suryavanshi , Sohel Mansur Shaikh , Ramnath Sominath Garje , Ms. Snehal Lad , Ms. Vaishnavi Katkar |
| Unique Id: | IJSDR2401088 |
| Published In: | Volume 9 Issue 1, January-2024 |
| Abstract: | The brain is the platform for our mental health. But there is a growing body of evidence, and a number of significant voices are championing the role of diet in the care and treatment of people with mental health problems. Ginkgo biloba leaf extract has shown beneficial effect in treating impairments in memory, cognitive speed, activities of daily living (ADL), edema, inflammation and free radical toxicity associated with traumatic brain injury (TBI), Alzheimer's dementia, stroke, vaso occlusive disorders, and aging. The purpose of this chapter is to provide the mechanisms of action, clinical indications, and safety of Ginkgo biloba extract (GBE). Ginkgo biloba (Gb) has demonstrated antioxidant and vasoactive properties as well as clinical benefits in several conditions such as ischemia, epilepsy, and peripheral nerve damage. Additionally, Gb is supposed to act as potential cognitive enhancer in dementia. So far, several trials have been conducted to investigate the potential effectiveness of Gb in neuropsychiatric conditions. However, the results of these studies remain controversial. We conducted a systematic review and a meta-analysis of three randomised controlled trials in patients with schizophrenia and eight randomised controlled trials in patients with dementia. Gb treatment reduced positive symptoms in patients with schizophrenia and improved cognitive function and activities of daily living in patients with dementia. No effect of Gb on negative symptoms in schizophrenic patients was found. The general lack of evidence prevents drawing conclusions regarding Gb effectiveness in other neuropsychiatric conditions (i.e., autism, depression, anxiety, attention-deficit hyperactivity disorder, and addiction). Our data support the use of Gb in patients with dementia and as an adjunctive therapy in schizophrenic patients. |
| Keywords: | Ginkgo biloba, Pharmacology, Memory impairment, Safety issues, Dosage forms, Anti oxidants. |
| Cite Article: | "A DETAIL OVERVIEW ON PHYTOCHEMISTRY, PHARMACOGNOSY AND PHARMACOLOGY OF MAIDENHAIR TREE (Ginkgo biloba L).", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.9, Issue 1, page no.617 - 624, January-2024, Available :http://www.ijsdr.org/papers/IJSDR2401088.pdf |
| Downloads: | 000338719 |
| Publication Details: | Published Paper ID: IJSDR2401088 Registration ID:209942 Published In: Volume 9 Issue 1, January-2024 DOI (Digital Object Identifier): Page No: 617 - 624 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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