Pharmacovigilance: A Cross-Sectional Hospital Base Research Survey on Antihypertensive Drugs and their Adverse Drug Reaction

Tushar Bhatkar , Purvesh Kewati , Prajwal Niwal , Preet Zatale , Pramod Burakale

Calcium Channel Blockers, Amlodipine, Metoprolol (Beta Blockers), Telmisartan-40 Mg, Angiotensin Receptor Blockers (ARBS), Antihypertensive Medications.

Aim: The study's goals were to identify and document adverse drug reactions (ADRs) in adult male and female patients as well as elderly patients receiving antihypertensive medication treatment at the Super Speciality Hospital in Amravati. Methods: Using in-patients at a Super Speciality Hospital, we conducted a three-month survey-based cross-sectional study. Patients were included based on predetermined criteria, and GraphPad Prism and Microsoft Excel 7 were used for data analysis. Results: The study highlights how important it is to use drug usage and prescription pattern surveys to comprehend how medications affect society. It shows that during combination therapy for antihypertensive agents, there is a greater incidence of essential hypertension in men and a rise in adverse drug reactions (ADRs), particularly in women, such as sweating and weakness. Commonly administered antihypertensive telmisartan exhibits notable adverse drug reactions (ADRs), underscoring the need for customised treatment regimens and close observation in addition to blood pressure management. All things considered, the results offer insightful information for tailored treatment, illuminating the intricate dynamics of drug use and its effects. Conclusion: To sum up, telmisartan has become the most often prescribed angiotensin II receptor blocker (ARB) within its respective category. Adverse drug reactions (ADRs) were notably more common in females, with frequent reports of headache, nausea, weakness, sweating, and dizziness. After analysing the demographic information, co-morbidities, use of ARBs, and the variety of ADRs linked to different ARBs in research participants, it was evident that improving ADR management and preventive measures can greatly improve treatment outcomes for patients.

Published Paper   E-Certificate

"Pharmacovigilance: A Cross-Sectional Hospital Base Research Survey on Antihypertensive Drugs and their Adverse Drug Reaction", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.9, Issue 2, page no.265 - 270, February-2024, Available :https://ijsdr.org/papers/IJSDR2402038.pdf

Volume 9 Issue 2, February-2024

Pages : 265 - 270

Paper Reg. ID: IJSDR_210081

Published Paper Id: IJSDR2402038

Downloads: 000347300

Research Area: Health Science 

Country: Amravati, Maharashtra, India

Published Paper PDF: https://ijsdr.org/papers/IJSDR2402038

Published Paper URL: https://ijsdr.org/viewpaperforall?paper=IJSDR2402038

ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJSDR(IJ Publication) Janvi Wave

This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition