Wound Healing: A Review of Mechanisms, Interventions, and Future Trends

Sanjay S , Sivakumar S , Jayaprakash S , Mohamed Shalim Khan

Keywords: wound healing, chronic wounds, special populations, biomaterials, tissue engineering, growth factors, stem cell therapy.

ABSTRACT: Wound healing is a complex biological process essential for the restoration of tissue integrity and function. This review provides a comprehensive overview of the mechanisms, factors, and interventions involved in wound healing, with a focus on chronic wound management and special populations. The phases of wound healing, including hemostasis, inflammation, proliferation, and remodeling, are discussed, highlighting the cellular and molecular mechanisms mediated by platelets, immune cells, cytokines, and growth factors. Factors influencing wound healing, such as patient-related, local, and systemic factors, are examined for their impact on healing outcomes. Various wound healing techniques and interventions, including dressings, surgical procedures, and emerging technologies like stem cell therapy and growth factor therapy, are explored. Chronic wound management is addressed, emphasizing the challenges and multidisciplinary approaches required for effective care. Special populations, including pediatric and geriatric patients, as well as those with specific conditions like diabetes and autoimmune diseases, are considered for their unique wound healing characteristics and needs. Additionally, the role of biomaterials and tissue engineering in promoting wound repair and regeneration is discussed, highlighting the use of scaffolds, matrices, and bioactive materials. Future directions in wound healing research are also outlined, focusing on advancements in technology, potential breakthroughs, and challenges in improving wound care outcomes. This review provides valuable insights for clinicians and researchers, emphasizing the importance of understanding wound healing processes to enhance patient care and outcomes.

Published Paper   E-Certificate

"Wound Healing: A Review of Mechanisms, Interventions, and Future Trends", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.9, Issue 3, page no.982 - 991, March-2024, Available :https://ijsdr.org/papers/IJSDR2403137.pdf

Volume 9 Issue 3, March-2024

Pages : 982 - 991

Paper Reg. ID: IJSDR_210588

Published Paper Id: IJSDR2403137

Downloads: 000347389

Research Area: Pharmacy

Country: Coimbatore, Tamil Nadu, India

Published Paper PDF: https://ijsdr.org/papers/IJSDR2403137

Published Paper URL: https://ijsdr.org/viewpaperforall?paper=IJSDR2403137

ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJSDR(IJ Publication) Janvi Wave

This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition