SYNTHESIS,CHARACTERIZATION AND PHARMACOLOGICAL ACTIVITY OF NEWLY SYNTHESIZED N-[2-(1H-BENZIMIDAZOL-2-YL)PHENYL]THIOUREA DERIVATIVES BY MICROWAVE ASSISTED TECHNIQUE
Gaikwad Shital D.
, Kale Pranali A.
Anti-Microbial, Anti-fungal, Microwave, phenylthiourea, pharmacophore.
The microwave-assisted synthesis is a unique and simple technique which offers fast and efficient processing of materials with higher reproducibility. Benzimidazole ring is an important pharmacophore in modern drug discovery. The titled compund were synthesized from substituted phenylthiourea oxidation by bromine water in acidic medium. Thiourea are important sulphur and nitrogen containing compound. Some of them derivatives posses valuable antifungal and antimicrobial activity. The process of alignment or orientation of molecules by the external electrical field may result in the production of internal heat which is responsible for a reduction in processing time and energy required. It is especially due to the heating homogeneity of microwaves. Microwave assisted method has several advantages shorter reaction times compared with other methods, higher yields, or very good reproducibility.
"SYNTHESIS,CHARACTERIZATION AND PHARMACOLOGICAL ACTIVITY OF NEWLY SYNTHESIZED N-[2-(1H-BENZIMIDAZOL-2-YL)PHENYL]THIOUREA DERIVATIVES BY MICROWAVE ASSISTED TECHNIQUE ", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.10, Issue 9, page no.a26-a44, September-2025, Available :https://ijsdr.org/papers/IJSDR2509005.pdf
Volume 10
Issue 9,
September-2025
Pages : a26-a44
Paper Reg. ID: IJSDR_304774
Published Paper Id: IJSDR2509005
Downloads: 00092
Research Area: Science and Technology
Country: -, -, India
ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: IJSDR(IJ Publication) Janvi Wave
