Carrier Screening Program for β-Thalassaemia and Other Haemoglobinopathies in Married and Pregnant Indian Women: Experience of 19767 Cases at Block level Hospitals of Nadia District in West Bengal and a Guideline for Screening and Diagnosis.

Rabindra Nath Halder , Nimai Chandra Mondal , Anirban Roy Chowdhury , Shakuntala Ghose , Amit Chakravarty,Sudipa Chakravarty

Thalassemia trait, Pregnancy, Haemoglobinopathies.

To control birth of thalassaemia major children by identification of risk couples prenatal diagnosis has been recommended. To study the prevalence of β thalassaemia trait in pre-pregnancy and pregnancy in population screening for β thalassaemia has been conducted for a period of 10 years. Blood samples were tested for complete blood count and HPLC. We present our experience of married and antenatal thalassaemia screening in block level district hospitals of Nadia district of West Bengal in India. All antenatal women presenting in those hospitals over 10 years were counselled for beta thalassaemia and other haemoglobinopathy screening. If the married woman was detected heterozygous for thalassaemia/haemoglobinopathy, partner screening was advised. If the husband was also detected to be heterozygous, the risk couple was offered prenatal diagnosis. A total of 3831 married and 14211 antenatal women were counselled for beta thalassaemia and for other haemoglobinopathy, with compliance in all the cases. Beta Thalassaemia heterozygosity was detected in 500 (29.1%) cases, HbE traits in 712 (41,4%) and other haemoglobin variants in 506(29.5%). The economic burden to the society for treating thalassaemic patients is huge. The institution of prevention programs like carrier screening has proven cost-effective in populations with a high frequency of carriers. Screening of pregnant women early in pregnancy followed by prenatal diagnosis is acceptable and effective strategy for control of thalassaemia in developing countries like India.

Published Paper   E-Certificate

"Carrier Screening Program for β-Thalassaemia and Other Haemoglobinopathies in Married and Pregnant Indian Women: Experience of 19767 Cases at Block level Hospitals of Nadia District in West Bengal and a Guideline for Screening and Diagnosis.", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.10, Issue 9, page no.b104-b109, September-2025, Available :https://ijsdr.org/papers/IJSDR2509116.pdf

Volume 10 Issue 9, September-2025

Pages : b104-b109

Paper Reg. ID: IJSDR_304958

Published Paper Id: IJSDR2509116

Downloads: 00065

Research Area: Science and Technology

Country: -, -, India

Published Paper PDF: https://ijsdr.org/papers/IJSDR2509116

Published Paper URL: https://ijsdr.org/viewpaperforall?paper=IJSDR2509116

ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJSDR(IJ Publication) Janvi Wave

This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition