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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | DEVELOPMENT OF INVASOMAL GEL FOR THE TREATMENT OF ACNE VULGARIS |
| Authors Name: | Mr.Rohit Dharmadas Zoad , Prof.Bhutada Chetan , Mr. Tushar P. Akhare , Dr. Lahu D. Hingane , Miss Shruti Ravindra Thakre |
| Unique Id: | IJSDR2308065 |
| Published In: | Volume 8 Issue 8, August-2023 |
| Abstract: | The most common skin issue from a variety of causes, acne vulgaris—commonly known as acne—has a higher frequency in teens. As a result of androgen-induced increased sebum production, altered keratinization, inflammation, and Propionibacterium acnes bacterial colonization of hair follicles on the face, neck, chest, and back, acne is a chronic inflammatory illness of the pilosebaceous unit. Seborrhoea (excess grease), non-inflammatory lesions (open and closed comedones), inflammatory lesions (papules and pustules), and varying degrees of scarring are some of the clinical characteristics of acne. One prospective research of 133 kids aged 5.5 to 12 years, followed for an average of 2.5 years, discovered that at first, just a small number of glands in the face were producing sebum, but as time went on, more and more glands began to do so. Unsaturated phosphatidyl choline, a minor amount of ethanol, and a small quantity of a blend of terpenes (cinnamic acid, citral, and d-limonene) made up the invadesomes. In an ethanolic phospholipid solution, the drug is combined with terpenes, or terpene combinations, for dissolution. To get a clear solution, the mixture is vortexed for 5 min, followed by 5 min of sonication. Phosphate buffer saline (PBS) (pH: 7.4) is continuously injected into the solution using a syringe. |
| Keywords: | Acne vulgaris, CAME, Invasomal gel |
| Cite Article: | "DEVELOPMENT OF INVASOMAL GEL FOR THE TREATMENT OF ACNE VULGARIS", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 8, page no.448 - 460, August-2023, Available :http://www.ijsdr.org/papers/IJSDR2308065.pdf |
| Downloads: | 000338720 |
| Publication Details: | Published Paper ID: IJSDR2308065 Registration ID:208150 Published In: Volume 8 Issue 8, August-2023 DOI (Digital Object Identifier): Page No: 448 - 460 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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